Title of article
Synthesis of chiral N-protected 1,2-dihydro-quinoline-2-carbonitrile and 1,2-dihydro-isoquinoline-1-carbonitrile via an asymmetric Reissert reaction
Author/Authors
Pauvert، نويسنده , , Mickaël and Collet، نويسنده , , Sylvain C. and Bertrand، نويسنده , , Marie-Jo and Guingant، نويسنده , , André Y. and Evain، نويسنده , , Michel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
2983
To page
2987
Abstract
Addition of cyanide ion to chiral N-acyl-quinolinium and N-acyl-isoquinolinium salts led selectively to 1,2-addition products. Removal of the chiral auxiliary affords the title compounds in pure enantiomeric form.
Keywords
2-dihydro-isoquinoline-1-carbonitrile , N-protected 1 , 2-dihydro-quinoline-2-carbonitrile , Chiral oxazolidinone-derived auxiliary , N-protected 1 , Asymmetric Reissert reaction
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845474
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