Title of article :
Pegylation of 1,4,8,11-tetraazacyclotetradecane (cyclam) and its Cu(II) complexation
Author/Authors :
Stephan، نويسنده , , Holger and Geipel، نويسنده , , Gerhard and Appelhans، نويسنده , , Dietmar and Bernhard، نويسنده , , Gert and Tabuani، نويسنده , , Daniela and Komber، نويسنده , , Hartmut and Voit، نويسنده , , Brigitte، نويسنده ,
Abstract :
Two novel star-like cyclam derivatives appended with four amino groups and four PEG-arms have been synthesised. The complex formation of cyclam and the two cyclam derivatives with Cu(II) has been studied by UV–vis and time-resolved laser-induced fluorescence (TRLFS) measurements outlining 1:1 complexes between cyclam ligands and Cu(II). By TRLFS measurements a quench effect of the Cu(II) on the fluorescence of the ligand was also found to determine the complex formation between Cu(II) and the ligands.
Keywords :
Cyclam , Synthesis , Complex formation , fluorescence
