Title of article :
Stereoselective synthesis of cis- and trans-2,3-disubstituted eight-membered medium-ring ethers based on Ireland–Claisen rearrangement of 3-alkoxy-2-propenyl glycolate esters and ring-closing olefin metathesis
Author/Authors :
Fujiwara، نويسنده , , Kenshu and Goto، نويسنده , , Akiyoshi and Sato، نويسنده , , Daisuke and Kawai، نويسنده , , Hidetoshi and Suzuki، نويسنده , , Takanori، نويسنده ,
Abstract :
A simple stereoselective synthesis of cis- and trans-2,3-disubstituted medium-sized cyclic ethers has been developed based on geometry-selective synthesis of 3-alkoxy-2-propenyl glycolate esters, Ireland–Claisen rearrangement of the glycolate esters, and ring-closing olefin metathesis.
