Title of article
A new synthesis of 4-oxygenated β-carboline derivatives by Fischer indolization
Author/Authors
Suzuki، نويسنده , , Hideharu and Tsukakoshi، نويسنده , , Yoshiyuki and Tachikawa، نويسنده , , Takuya and Miura، نويسنده , , Yuusuke and Adachi، نويسنده , , Makoto and Murakami، نويسنده , , Yasuoki Murakami، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
3831
To page
3834
Abstract
A new and short synthetic route to the 4-methoxy-β-carboline skeleton is described. The route involves Fischer indolization of enehydrazine of 1-tosylpiperidine-3,5-dione and successive acetalization–elimination for aromatization of 1,2,3,4-tetrahydro-2-tosyl-9H-β-carbolin-4-one. This method is efficiently applicable to synthesis of the benzene-part substituted 4-oxygenated β-carboline derivatives.
Keywords
indole , Acetalization , Fischer indolization , aromatization , ?-Carboline
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845793
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