Title of article :
Skeletal rearrangements of bicyclo[2.2.2]lactones: a short and efficient route towards Corey’s lactone
Author/Authors :
Augustyns، نويسنده , , Beno?ˆt and Maulide، نويسنده , , Nuno and Mark?، نويسنده , , Istv?n E.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
The application of a unique tandem radical-initiated, Brönsted acid-catalysed, skeletal rearrangement of bicyclo[2.2.2]lactones provides a novel route towards Corey’s lactone 2. The strategy also features a high-pressure promoted inverse electron-demand Diels–Alder (IEDDA) reaction of 3-carbomethoxy-2-pyrone (3-CMP), which proceeds with complete regio- and diastereocontrol.
Keywords :
bicyclic , Lactones , radical , Corey’s lactone , 3-CMP , Diels–Alder , Rearrangement
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
