Title of article
Synthesis of macrocyclic 1,1′-biarenol derivatives by the tandem Claisen rearrangement and their binding properties
Author/Authors
Yoshida، نويسنده , , Hiroaki and Kobayashi، نويسنده , , Yuka and Hiratani، نويسنده , , Kazuhisa and Saigo، نويسنده , , Kazuhiko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
3901
To page
3904
Abstract
Crown ether-type macrocycles consisting of an enantiopure biarenol derivative and an oligoethylene glycol were synthesized by the Lewis acid-mediated tandem Claisen rearrangement. This is the first example of the successful application of the tandem Claisen rearrangement to the synthesis of enantiopure macrocyclic biarenol derivatives. The enantiopure macrocyclic biarenols were found to form 1:1 complexes with amino acid salts and to discriminate their chirality.
Keywords
1?-Bi-2-naphthol , Chiral recognition , Amino acid salt , tandem Claisen rearrangement , 1 , Host–guest complex
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845820
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