Title of article :
A simpler and greener protocol for the preparation of β-acetylamino ketones by a one-pot reaction of aryl aldehydes, enolisable ketones, acetyl chloride and acetonitrile in the presence of zeolite Hβ as a reusable catalyst
Author/Authors :
Bhat، نويسنده , , Ramakrishna P. and Raje، نويسنده , , Vivek P. and Alexander، نويسنده , , Varughese M. and Patil، نويسنده , , Sachin B. and Samant، نويسنده , , Shriniwas D.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
β-Acetylamino ketones have been obtained in a one-pot coupling of an aldehyde with an enolisable ketone, acetyl chloride and acetonitrile in the presence of zeolite Hβ as catalyst at room temperature (26–28 °C). The procedure has the advantages of mild workup, circumvention of high temperature and inert atmosphere. The catalyst was found to be recyclable.
Keywords :
one-pot synthesis , ?-Acetylamino ketones , multicomponent reaction , H? catalyst
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
