Title of article :
Synthesis of a novel series of 4,4-disubstituted 2,3,4,7-tetrahydroazepines
Author/Authors :
Barberis، نويسنده , , Mario and Garcيa-Losada، نويسنده , , Pablo and Pleite، نويسنده , , Sehila and Rodrيguez، نويسنده , , Juan Ramَn and Soriano، نويسنده , , José Francisco and Mendiola، نويسنده , , Javier، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
A general, simple and straightforward strategy for the synthesis of a novel series of 4,4-disubstituted 2,3,4,7-tetrahydroazepines is described. This route involves a one-pot Wittig olefination/N-allylation process on a five-membered hemi-aminal followed by a final ring closing metathesis reaction.
Keywords :
azepine , metathesis , Pyrrolidinone , Wittig
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
