Title of article :
Synthesis of a boronated amino acid as a potential neutron therapy agent: 1-amino-3-[(dihydroxyboryl)ethyl]cyclobutanecarboxylic acid
Author/Authors :
Kabalka، نويسنده , , George W. and Yao، نويسنده , , Min-Liang and Navarane، نويسنده , , Abhijit، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
A novel boronated aminocyclobutanecarboxylic acid was synthesized in 10 steps for potential use in neutron capture therapy. The molecule was modeled after the unnatural amino acid 1-aminocyclobutanecarboxylic acid, which has shown high uptake in brain tumors.
Keywords :
Amino acid , Cyclobutane derivative , Amine borane , Boronic Acid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
