Title of article :
Direct mono-phosphorylation of 1,3-diols. A synthesis of FTY720-phosphate
Author/Authors :
Takeda، نويسنده , , Shuzo and Chino، نويسنده , , Masao and Kiuchi، نويسنده , , Masatoshi and Adachi، نويسنده , , Kunitomo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
A novel method for selective and direct phosphorylation of various 1,3-diols using silver(I) oxide, tetrabenzyl pyrophosphate (TBPP), and tetrahexylammonium iodide affording mono-phosphates was developed. We applied the present method to the synthesis of FTY720-phosphate.
Keywords :
FTY720 , Mono-phosphorylation , 1 , Silver(I) oxide , 3-diol , Tetrabenzyl pyrophosphate (TBPP) , Tetrahexylammonium iodide
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
