Title of article :
Nickel-mediated carboxylative cyclization of enynes
Author/Authors :
Takimoto، نويسنده , , Masanori and Mizuno، نويسنده , , Takashi and Sato، نويسنده , , Yoshihiro and Mori، نويسنده , , Miwako، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Nickel-mediated carboxylative cyclization of α,ω-enyne using carbon dioxide was investigated. Oxidative cycloaddition of enynes having an electron withdrawing group on alkene to a zero-valent nickel complex smoothly proceeded to provide nickelacyclopentene intermediates, which regioselectively reacted with CO2 at the Csp3–nickel bond, giving cyclized carboxylation products in good yields.
Keywords :
nickel , Carboxylation , cyclization , Carbon dioxide
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
