Title of article :
Total synthesis of (−)-microcarpalide from d-mannitol
Author/Authors :
Ghosh، نويسنده , , Subhash and Rao، نويسنده , , R. Vengal and Shashidhar، نويسنده , , J.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
The total synthesis of the actin-targeting metabolite (−)-microcarpalide is described. Ring-closing metathesis of a dienic ester was used as the key step. d-Mannitol was used as the chiral pool material for the construction of the olefinic acid moiety as well as the olefinic alcohol moiety of the molecule.
Keywords :
ring-closing metathesis , d-Mannitol , Microcarpalide , allylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
