Author/Authors :
Shoji، نويسنده , , Muneo and Shiohara، نويسنده , , Kaoru and Oikawa، نويسنده , , Masato and Sakai، نويسنده , , Ryuichi and Sasaki، نويسنده , , Makoto، نويسنده ,
Abstract :
Synthesis of dysiherbaine analogue 4, which corresponds to 8,9-epi-neodysiherbaine A, is described. The synthesis features a concise route to the bicyclic ether skeleton through stereoselective C-glycosylation to set the C6 stereocenter and 5-exo ring-closure to form the tetrahydrofuran ring. The results of preliminary biological studies of 4 are also provided.
