Title of article
Selective bifunctionalization of pyrido[2,3-d]pyrimidines in positions 2 and 4 by SNAr and palladium-catalyzed coupling reactions
Author/Authors
Lavecchia، نويسنده , , G. and Berteina-Raboin، نويسنده , , S. and Guillaumet، نويسنده , , G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
5851
To page
5855
Abstract
Selective disubstitution of 2,4-dichloropyrido[2,3-d]pyrimidine with various nucleophiles was investigated. Suzuki and Stille cross-coupling reactions on monosubstituted compound 4-tert-butylamino-2-chloro-pyrido[2,3-d]pyrimidine were performed in high yields.
Keywords
Suzuki reaction , cross-coupling , Stille reaction , PALLADIUM , 3-d]pyrimidine , SNAr
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846510
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