Author/Authors :
Dong، نويسنده , , Hua and Zhang، نويسنده , , Zhi-Liu and Huang، نويسنده , , Jia-Hui and Ma، نويسنده , , Rujian and Chen، نويسنده , , Shu-Hui and Li، نويسنده , , Ge، نويسنده ,
Abstract :
A convergent synthesis of aliskiren was accomplished via the use of Segment AB as the key intermediate, which was prepared via the coupling of the Grignard reagent derived from Segment B with Segment A, followed by subsequent oxidative lactonization.