Author/Authors :
Yin، نويسنده , , Wenyuan and Sarma، نويسنده , , P.V.V. Srirama and Ma، نويسنده , , Jun and Han، نويسنده , , Dongmei and Chen، نويسنده , , Jessica L. and Cook، نويسنده , , James M.، نويسنده ,
Abstract :
The first synthesis of bivalent ligands of β-carboline-3-carboxylates has been achieved from β-carboline-3-carboxylate tert-butyl ester (βCCt) via Sonogashira and palladium-catalyzed homocoupling processes. The Boc protected intermediate, an iodo-β-carboline-3-carboxylate, was employed to provide a general entry into a series of bivalent ligands structurally similar to βCCt.
Keywords :
Bivalent ligands , Homocoupling , ?-Carbolines , ?CCt
