Title of article
Improved synthesis of quinine alkaloids with the Teoc protective group
Author/Authors
Igarashi، نويسنده , , Junji and Kobayashi، نويسنده , , Yuichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
6381
To page
6384
Abstract
TeocCl (Teoc: C(O)O(CH2)2TMS) generated in situ was conveniently used for trans-protection of the N-Bn piperidine intermediate to N-Teoc piperidine. Later, deprotection of the Teoc group and the subsequent quinuclidine ring formation was achieved with CsF in a domino fashion to afford the quinine alkaloids.
Keywords
Teoc , CSF , Protective group , Nitrogen atom , Quinidine , Quinine
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846636
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