• Title of article

    Improved synthesis of quinine alkaloids with the Teoc protective group

  • Author/Authors

    Igarashi، نويسنده , , Junji and Kobayashi، نويسنده , , Yuichi، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    6381
  • To page
    6384
  • Abstract
    TeocCl (Teoc: C(O)O(CH2)2TMS) generated in situ was conveniently used for trans-protection of the N-Bn piperidine intermediate to N-Teoc piperidine. Later, deprotection of the Teoc group and the subsequent quinuclidine ring formation was achieved with CsF in a domino fashion to afford the quinine alkaloids.
  • Keywords
    Teoc , CSF , Protective group , Nitrogen atom , Quinidine , Quinine
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2005
  • Journal title
    Tetrahedron Letters
  • Record number

    1846636