Author/Authors :
Kawasaki، نويسنده , , Ikuo and Terano، نويسنده , , Masami and Kurume، نويسنده , , Ai and Hara، نويسنده , , Satoko and Yamashita، نويسنده , , Masayuki and Ohta، نويسنده , , Shunsaku، نويسنده ,
Abstract :
Reaction of 1-substituted 3-alkenyl-1H-indoles with an equimolar amount of trifluoroacetic acid in dichloromethane gave cyclic dimers, 1,3-trans-N,N′-disubstituted cyclopent[b]indoles, in 53–84% yields as sole products through an acid-mediated stereoselective cyclo-dimerization process. The structure of the cyclic dimer derived from 3-cyclopentylidenemethyl-1-methyl-1H-indole was elucidated by X-ray crystallographic analysis.
