Title of article :
Synthesis of 3,4-disubstituted piperidines by ene cyclisation of 4-aza-1,7-dienes
Author/Authors :
Walker، نويسنده , , Stephen M. and Williams، نويسنده , , Jodi T. and Russell، نويسنده , , Alexander G. and Snaith، نويسنده , , John S.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Ene cyclisation of a variety of 4-aza-1,7-dienes affords 3,4-disubstituted piperidines. In particular, cyclisation of diesters 14 and 20 catalysed by MeAlCl2 gives the corresponding trans 3,4-disubstituted piperidines with diastereomeric ratios of >200:1.
Keywords :
Piperidine , Ene , Cyclisation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
