Title of article :
Asymmetric synthesis of the pyran antibiotic (−)-centrolobine
Author/Authors :
Chandrasekhar، نويسنده , , S. and Prakash، نويسنده , , S. Jaya and Shyamsunder، نويسنده , , T.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
An expedient total synthesis of (−)-centrolobine is achieved involving asymmetric Keck allylation and stereoselective intramolecular oxy-Michael reactions as key steps in 8% overall yield.
Keywords :
(?)-Centrolobine , 2 , Intramolecular oxy-Michael reaction , Keck allylation , 6-Disubstituted tetrahydropyran
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters