Author/Authors :
Comins، نويسنده , , Daniel L. and Nolan، نويسنده , , Jason M. and Bori، نويسنده , , Ibrahim D.، I. نويسنده Department of Biology, Zamfara State College of Education Maru, Pmb 1002, Maru, Zamfara State, Nigeria. Ibrahim D., I.
Abstract :
Lithium–halogen exchange of 2,4-dibromoquinolines proceeds regioselectively at C-4 and affords 4-substituted quinolines on quenching with electrophiles. Palladium-catalyzed cross-coupling reactions of 2-bromo-4-iodoquinoline provide 4-substituted 2-bromoquinoline derivatives.
Keywords :
Lithium–halogen exchange , Quinolines , cross-coupling , ?-Amino alkoxide
