Title of article :
A direct transformation of O-silyl groups into O-trichloroacetates. A novel synthetic approach to protein kinase C ligands: 1-oleoyl-2-acetyl- and 1-hexadecyl-2-acetyl-sn-glycerols
Author/Authors :
Stamatov، نويسنده , , Stephan D. and Kullberg، نويسنده , , Martin and Stawinski، نويسنده , , Jacek، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
A fluoride ion-promoted direct esterification of tert-butyldimethylsilyl- (TBDMS), or triisopropylsilyl (TIPS)-protected glycerol derivatives by means of trichloroacetic anhydride (TCAA), followed by removal of the trichloroacetyl transient protection, provides a new, efficient entry to stereochemically pure 1-oleoyl-2-acetyl- and 1-O-hexadecyl-2-acetyl-sn-glycerols.
Keywords :
Diglycerides , 1-O-Hexadecyl-2-acetyl-sn-glycerol , Trichloroacetic anhydride , Triethylamine tris(hydrofluoride) , 1-Oleoyl-2-acetyl-sn-glycerol , Protein kinase C ligands
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
