Title of article
Efficient method for the direct preparation of amides from carboxylic acids using tosyl chloride under solvent-free conditions
Author/Authors
Khalafi-Nezhad، نويسنده , , Ali and Parhami، نويسنده , , Abolfath and Soltani Rad، نويسنده , , Mohammad Navid and Zarea، نويسنده , , Abdolkarim، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
6879
To page
6882
Abstract
A simple, clean and highly efficient solvent-free procedure for the preparation of primary, secondary, tertiary and aromatic amides is described from the direct reaction of carboxylic acids and silica-supported ammonium salts, triethylamine (TEA) and tosyl chloride (TsCl) as condensing agent. The reaction proceeds rapidly in high yields at room temperature.
Keywords
amide , solvent-free , Ammonium salts , Tosyl chloride
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846806
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