Title of article
Efficient fluoride-mediated synthesis of 5-alkyl amino- and ether-substituted pyrazoles
Author/Authors
Andrei Shavnya، نويسنده , , Andrei and Sakya، نويسنده , , Subas M. and Minich، نويسنده , , Martha L. and Rast، نويسنده , , Bryson and Lundy DeMello، نويسنده , , Kristin and Jaynes، نويسنده , , Burton H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
6887
To page
6891
Abstract
Fluoride-mediated nucleophilic substitution reactions of 1-(4-methylsulfonyl (or sulfonamido)-2-pyridyl)-5-chloro-4-cyano pyrazoles with various amines and alcohols occur under mild conditions to provide the 5-alkyl amino and ether pyrazoles in moderate to high yields.
Keywords
Cox-2 inhibitors , Fluoride mediated , pyrazoles
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846809
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