Author/Authors :
Sajiki، نويسنده , , Hironao and Ito، نويسنده , , Nobuhiro and Esaki، نويسنده , , Hiroyoshi and Maesawa، نويسنده , , Tsuneaki and Maegawa، نويسنده , , Tomohiro and Hirota، نويسنده , , Kosaku، نويسنده ,
Abstract :
An effective and applicable Pt/C-catalyzed deuteration method of aromatic rings using D2O as a deuterium source under hydrogen atmosphere was developed. Five percent Pt/C would lead to quite effective H–D exchange results on the aromatic ring systems. The reaction is general for a variety of aromatic compounds including biologically active compounds.
Keywords :
H–D exchange , Deuterium , Pt/C , Aromatic ring , Hydrogenation
