Title of article :
Improved synthesis of functionalized 5,6-dihydro-pyrimido[4,5-b][1,4]oxazepines
Author/Authors :
Xu، نويسنده , , Yongjiang and Liu، نويسنده , , Hu and Pan، نويسنده , , Weitao and Chen، نويسنده , , Xin and Wong، نويسنده , , Wai C. and Labelle، نويسنده , , Marc، نويسنده ,
Abstract :
Novel synthetic approaches toward 5,6-dihydro-pyrimido[4,5-b][1,4]oxazepines were reported that led to successful introduction of poorly reactive anilines and various 2-hydroxybenzaldehydes to this therapeutically relevant scaffold. More extensive SAR studies on this scaffold hence became possible.
