Author/Authors :
Braga، نويسنده , , Antonio L. and Lüdtke، نويسنده , , Diogo S. and Schneider، نويسنده , , Paulo H. and Vargas، نويسنده , , Fabricio and Schneider، نويسنده , , Alex and Wessjohann، نويسنده , , Ludger A. and Paixمo، نويسنده , , Mلrcio W.، نويسنده ,
Abstract :
Pyrrolidinylmethanols, easily accessible from readily available (S)-proline, were applied in zinc-catalyzed addition of arylboronic acids to aromatic aldehydes; the reaction was found to proceed in excellent yields and high enantioselectivities (up to 98% ee).
Keywords :
Diarylmethanols , Asymmetric catalysis , Zinc , Boronic acids , proline