Title of article
Total synthesis of (±)-cyclooroidin
Author/Authors
Gianluca Papeo، نويسنده , , Gianluca and Frau، نويسنده , , Marيa Antonia Gَmez-Zurita and Borghi، نويسنده , , Daniela and Varasi، نويسنده , , Mario، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
8635
To page
8638
Abstract
The first total synthesis of (±)-cyclooroidin, a member of the pyrrole–imidazole alkaloid family recently isolated from the sponge Agelas oroides in optically pure form, is described. The synthesis was achieved in nine linear steps, with an overall yield of 10%. Key step was a Wolff bromoketone synthesis performed on the intermediate longamide B.
Keywords
pyrrole–imidazole alkaloids , Cyclooroidin , Wolff bromoketone synthesis
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1847824
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