Title of article
Direct aldol and tandem Mannich reactions in room temperature ammonia solutions
Author/Authors
Feng، نويسنده , , Lichun and Xu، نويسنده , , Lijin and Lam، نويسنده , , Kimhung and Zhou، نويسنده , , Zhongyuan and Yip، نويسنده , , C.W. and Chan، نويسنده , , Albert S.C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
8685
To page
8689
Abstract
An economical, simple, and efficient direct aldol reaction via the double activation of both aldehydes and ketones by ammonia has been developed. An unprecedented tandem Mannich reaction was observed when hydroxybenzaldehydes, pyrrole-2-carboxyaldehyde, and indole-3-carboxyaldehyde were employed to afford 2,2-dimethyl-6-aryl-4-pyrilidinones in moderate to good yields.
Keywords
Mannich reaction , Ammonia solutions , aldol reaction , tandem
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1847836
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