Author/Authors :
Vvedensky، نويسنده , , Vladimir Y. and Rogovoy، نويسنده , , Boris V. and Kiselyov، نويسنده , , Alexander S. and Ivachtchenko، نويسنده , , Alexandre V.، نويسنده ,
Abstract :
We have developed a robust solid-phase approach to cyclic guanidines based on the Staudinger protocol. The synthetic sequence involves the reaction of the immobilized aza-Wittig reagents derived from the respective azidobenzoic acids with bifunctional amines. Convenient isolation and good yields of the desired products (34–84%) along with the diversity of the targeted molecules are distinctive features of the resultant library.
