Author/Authors :
Guha، نويسنده , , Samar Kumar and Wu، نويسنده , , Bo and Kim، نويسنده , , Beom Soo and Baik، نويسنده , , Woonphil and Koo، نويسنده , , Sangho، نويسنده ,
Abstract :
Various carbonyl compounds undergo α-bromination reaction under a mild and practical condition utilizing N-bromosuccinimide (NBS), catalyzed by trimethylsilyl trifluoromethanesulfonate (TMS·OTf). This method is also effective for the side-chain bromination of heteroaromatic carbonyl compounds without the ring brominations.