Author/Authors :
Zhang، نويسنده , , Xianshu and Da، نويسنده , , Shijun and Zhang، نويسنده , , Chaoxin and Xie، نويسنده , , Zhixiang and Li، نويسنده , , Ying، نويسنده ,
Abstract :
The first total synthesis of (3S,6R)-3,6-dihydroxy-10-methylundecanoic acid was accomplished from commercially available 1-bromo-3-methylbutane in 11 steps and 25.8% overall yield. The key steps were asymmetric allylic alkylations via allyldiisopinocampheylborane and hydroboration–oxidation.
