Author/Authors :
Toyooka، نويسنده , , Naoki and Dejun، نويسنده , , Zhou and Nemoto، نويسنده , , Hideo and Garraffo، نويسنده , , H. Martin and Spande، نويسنده , , Thomas F. and Daly، نويسنده , , John W.، نويسنده ,
Abstract :
Enantioselective syntheses of indolizidines (−)-219F and (−)-221I have been achieved and the relative stereochemistries of natural 219F and 221I were determined by the present synthesis. A levorotatory indolizidine, corresponding to one proposed structure for 193E, was also synthesized, but was found to differ from 193E. It seems likely that natural 193E is the 8-epimer of the synthesized indolizidine.
