Glycosylation of vanillin by amyloglucosidase in organic media

Glycosylation of vanillin using amyloglucosidase from a Rhizopus mold with d-glucose, d-galactose, d-mannose, maltose, sucrose and d-sorbitol in di-isopropyl ether yielded glycosides in the range 13–53%. NMR spectral data confirmed linking between the phenolic OH of vanillin and C1 and/or C6 of the carbohydrate moieties.