Title of article :
A six-step synthesis of (S)-5-ethenyl-3-(1-methyl-2-pyrrolidinyl)pyridine (SIB-1508Y) from (S)-nicotine
Author/Authors :
Comins، نويسنده , , Daniel L. and Smith، نويسنده , , Emilie D. Smith، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
The anti-Parkinson’s agent SIB-1508Y was prepared in six steps from (S)-nicotine in 20% overall yield. The strategy involves a regioselective formylation at C-5 of a 1,4-dihydronicotine intermediate.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
