Author/Authors :
Eklund، نويسنده , , Patrik and Holmstrِm، نويسنده , , Toni and Al-Ubaydy، نويسنده , , Lamis and Sjِholm، نويسنده , , Rainer and Hakala، نويسنده , , Juha، نويسنده ,
Abstract :
Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol.
