One-step reductive amidation of nitro arenes: application in the synthesis of Acetaminophen™
Author/Authors :
Bhattacharya، نويسنده , , Apurba and Purohit، نويسنده , , Vikram C. and Suarez، نويسنده , , Victor and Tichkule، نويسنده , , Ritesh and Parmer، نويسنده , , Gaurang and Rinaldi، نويسنده , , Frank، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Pages :
4
From page :
1861
To page :
1864
Abstract :
A novel thioacetate mediated one-step reductive acetamidation of aryl nitro compounds was developed and applied to an efficient synthesis of acetaminophen. The reaction also proceeds well without a solvent in the presence of a catalytic amount of surfactant.
