Title of article
A new and versatile Ugi/SNAr synthesis of fused 4,5-dihydrotetrazolo[1,5-a]quinoxalines
Author/Authors
Kalinski، نويسنده , , Cédric and Umkehrer، نويسنده , , Michael and Gonnard، نويسنده , , Sebastien and Jنger، نويسنده , , Nadine and Ross، نويسنده , , Günther and Hiller، نويسنده , , Wolfgang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
2041
To page
2044
Abstract
A combinatorial synthetic route yielding fused tetrazolo[1,5-a]quinoxalines is described. The use of 2-fluorophenylisocyanide in the Ugi-tetrazole reaction (tetrazole-U-4CR) followed by a nucleophilic aromatic substitution (SNAr) affords the tricylic tetrazolo[1,5-a]quinoxaline moiety in good yields and with high diversity.
Keywords
nucleophilic aromatic substitution , Ugi-reaction , Multi-component reaction , Fused tetrazoloquinoxaline , tetrazole
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849297
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