Title of article :
A synthetic approach to new polycyclic ring system of biological interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine
Author/Authors :
Lauria، نويسنده , , Antonino and Patella، نويسنده , , Chiara and Diana، نويسنده , , Patrizia and Barraja، نويسنده , , Paola and Montalbano، نويسنده , , Alessandra and Cirrincione، نويسنده , , Girolamo and Dattolo، نويسنده , , Gaetano and Almerico، نويسنده , , Anna Maria، نويسنده ,
Abstract :
The title indolo-triazolo-pyrimidines were obtained from 3-azidoindoles and can be used as models for the design of DNA-interactive compounds. Hetero-domino reaction of azidoindoles/pyrroles and acetonitriles constitutes the synthetic entry to annelated 1,2,3-triazolo[1,5-a]pyrimidines.