Title of article
Conversion of γ-substituted bicyclo[2.2.1] (Z)-vinylsulfones to the corresponding (E)-allylsulfones
Author/Authors
Cossu، نويسنده , , Sergio and Peluso، نويسنده , , Paola and Moretto، نويسنده , , Flavio and Marchetti، نويسنده , , Mauro، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
2253
To page
2256
Abstract
The preparation of bicyclo[2.2.1] (E)-allylsulfones starting from the corresponding (Z)-vinylsulfones is described. Starting from 2,3-bis(phenylsulfonyl)norbornadiene 1, the Michael addition of organometallic reagents followed by the base catalyzed isomerization affords (E)-allylsulfones in high yields. The procedure allows to obtain vinylidenic norbornenes which are characteristic nuclei of valuable biologically active compounds.
Keywords
Grignard reagents , Polycyclic alkenes , Vinylsulfones , alkene isomerization , Allylsulfones
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849385
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