Title of article :
CAN-mediated oxidative cleavage of 4-aryl-3,4-dihydroxypiperidines
Author/Authors :
Chang، نويسنده , , Meng-Yang and Lin، نويسنده , , Chun-Yu and Pai، نويسنده , , Chun-Li، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
A CAN-mediated oxidative cleavage of 4-aryl-3,4-dihydroxypiperidines 2Aa–Be to β-amino carbonyl compounds 3Aa–Be and 4Aa–Be in different ratios is described. This facile strategy was also used to synthesize racemic fluoxetine (5).
Keywords :
4-dihydroxypiperidines , 4-Aryl-3 , ?-Amino carbonyl compounds , Cerium ammonium nitrate , Fluoxetine , 4-Hydroxypiperidine
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
