Title of article :
Synthesis of a homotrifunctional conjugation reagent based on maleimide chemistry
Author/Authors :
Farha، نويسنده , , Omar K. and Julius، نويسنده , , Richard L. and Hawthorne، نويسنده , , M. Frederick، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
A novel homotrifunctional conjugation reagent, 1,3,5-tris-(N-maleimidomethyl)benzene has been synthesized in high yield with minimum purification. The reactivity of this compound was examined by using l-cysteine as a nucleophile.
Keywords :
3 , maleimide , Cysteine , Diels–Alder , Mitsunobu , thiol , Homotrifunctional conjugation reagent , 1 , 3 , 5-Tris(hydroxymethyl)benzene , 1 , 5-Tris-(N-maleimidomethyl)benzene
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
