Title of article
8-Azabicyclo[3.2.1]oct-3-en-2-ones via asymmetric 1,3-dipolar cycloaddition of a homochiral 3-oxidopyridinium betaine
Author/Authors
Curtis، نويسنده , , Neil R. and Ball، نويسنده , , Richard G. and Kulagowski، نويسنده , , Janusz J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
2635
To page
2638
Abstract
8-Azabicyclo[3.2.1]oct-3-en-2-ones were prepared by asymmetric 1,3-dipolar cycloadditions of homochiral pyridinium betaine 4. Excellent diastereofacial selectivity was achieved for the major 6-exo cycloadducts. The absolute stereochemistry of cycloadduct 7 was confirmed by a single-crystal X-ray diffraction study.
Keywords
asymmetric synthesis , 3-dipolar cycloaddition , 1 , diastereoselective , X-ray crystallography , 3-Oxidopyridinium betaine
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849601
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