Title of article :
TMSI mediated Prins-type cyclization of ketones with homoallylic and homopropargylic alcohol: synthesis of 2,2-disubstituted-, spirocyclic-4-iodo-tetrahydropyrans and 5,6-dihydro-2H-pyrans
Author/Authors :
Sabitha، نويسنده , , Gowravaram and Reddy، نويسنده , , K. Bhaskar and Bhikshapathi، نويسنده , , M. and Yadav، نويسنده , , J.S.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
The Prins-type cyclization of ketones with homoallylic and homopropargylic alcohols in the presence of TMSI generated in situ from TMSCl and NaI produced 2,2-disubstituted- or spirocyclic-4-iodo-tetrahydropyrans and spirocyclic-4-iodo-5,6-dihydro-2H-pyrans in good yields. These iodopyrans are reported for the first time.
Keywords :
6-Dihydro-2H-pyrans , Homoallylic alcohols , Homopropargylic alcohols , TMSI , Prins reaction , ketones , tetrahydropyrans , 5
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
