Author/Authors :
Qin، نويسنده , , Hong-Jian and Tian، نويسنده , , Wei-Sheng and Lin، نويسنده , , Cui-Wu Lin، نويسنده ,
Abstract :
22-Deoxy-OSW-1 (1), an analogue of OSW-1 with the potent anticancer activity, was synthesized by utilizing the intact skeleton of diosgenin in 11 steps in 13.7% overall yield. This synthesis demonstrated an effective and reasonable synthetic strategy for bioactive steroids with side chains.
