• Title of article

    A highly efficient synthesis of 22-deoxy-OSW-1 by utilizing the intact skeleton of diosgenin

  • Author/Authors

    Qin، نويسنده , , Hong-Jian and Tian، نويسنده , , Wei-Sheng and Lin، نويسنده , , Cui-Wu Lin، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2006
  • Pages
    3
  • From page
    3217
  • To page
    3219
  • Abstract
    22-Deoxy-OSW-1 (1), an analogue of OSW-1 with the potent anticancer activity, was synthesized by utilizing the intact skeleton of diosgenin in 11 steps in 13.7% overall yield. This synthesis demonstrated an effective and reasonable synthetic strategy for bioactive steroids with side chains.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2006
  • Journal title
    Tetrahedron Letters
  • Record number

    1849934