Title of article
Novel synthesis of α-arylnaphthalenes from diphenylacetaldehydes and 1,1-diphenylacetones
Author/Authors
Kozik، نويسنده , , Bart?omiej and Wilamowski، نويسنده , , Jaros?aw and G?ra، نويسنده , , Maciej and Sepio?، نويسنده , , Janusz J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
3435
To page
3438
Abstract
A two-step synthesis of 1-amino-4-arylnaphthalene-2-carbonitriles from diphenylacetaldehydes and 1,1-diphenylacetones involves condensation of the carbonyl compounds with malonodinitrile and cyclization of the aryl-ylidenemalonodinitriles obtained in concentrated sulfuric acid. The benzannulation reaction is accompanied with a quasi-aromatic rearrangement. Some of synthesized aminonitriles reveal considerable biological activity against phytopathogenic fungi.
Keywords
1-Arylnaphthalenes , Fungistatic activity , Aromatic aminonitriles , Rearrangement , cyclization
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850323
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