Title of article
Synthesis of cyclic peptides using a palladium-catalyzed enyne cycloisomerization
Author/Authors
Balraju، نويسنده , , V. and Dev، نويسنده , , R. Vasu and Reddy، نويسنده , , D. Srinivasa and Iqbal، نويسنده , , Javed، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
3569
To page
3571
Abstract
In this letter, we report a palladium-catalyzed enyne cycloisomerization of linear peptides to generate small cyclic peptides embedded with a conjugated 1,3-diene. The utility of these resulting macrocyclic dienes is demonstrated by carrying out [4+2] cycloadditions with dienophiles to generate constrained cyclic peptides with cyclic linkers.
Keywords
Peptidomimetics , Diels–Alder reaction , Enyne cycloisomerization , cyclic peptide
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850367
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