Title of article
Palladium mediated cycloisomerization of sugar alkynols: synthesis of cyclic enol-ethers and spiroketals
Author/Authors
Ramana، نويسنده , , C.V. and Mallik، نويسنده , , Rosy and Gonnade، نويسنده , , Rajesh G. and Gurjar، نويسنده , , Mukund K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
3649
To page
3652
Abstract
Functionalized bicyclic enol-ethers and spiroketals are prepared by Pd catalyzed cycloisomerization of 3-C-alkynylfuranosyl derivatives. Cycloisomerization of differently substituted alkyne derivatives revealed a preference for 6-endo-dig cyclization over 5-exo-dig if the substituent is not sufficiently electron withdrawing. The scope of these cycloisomerizations has been further extended by integrating with conjugate addition.
Keywords
PALLADIUM , cycloisomerization , C-alkynylfuranose , spiroketal , Enol-ether
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850406
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