Title of article
Synthesis of β-chloro α-amino acids: (2S,3R)- and (2S,3S)-3-chloroleucine
Author/Authors
Valls، نويسنده , , Nativitat and Borregلn، نويسنده , , Mar and Bonjoch، نويسنده , , Josep، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
5
From page
3701
To page
3705
Abstract
The first syntheses of (2S,3R)- and (2S,3S)-3-chloroleucine (3-chloro-d-leucines 1 and 2) have been achieved from d-3-hydroxyleucine and allo-d-3-hydroxyleucine, respectively, through the formation of the corresponding N-Cbz β-lactones, followed by a ring opening promoted by lithium chloride and a debenzylation process.
Keywords
?-Lactones , ?-Chloro ?-amino acids , Aeruginosins , 3-Chloroleucine , Ring opening
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850439
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