Author/Authors :
van den Hoogenband، نويسنده , , Adri and Lange، نويسنده , , Jos H.M. and Iwema-Bakker، نويسنده , , Wouter I. and den Hartog، نويسنده , , Jack A.J. and van Schaik، نويسنده , , Jord and Feenstra، نويسنده , , Rolf W. and Terpstra، نويسنده , , Jan Willem، نويسنده ,
Abstract :
An unprecedented synthetic approach to novel 4-aryl-1-methyloxindoles is described. The method involves the intramolecular palladium-catalyzed amidation of N-methyl-2,6-dibromophenylacetamide followed by an in situ Suzuki cross-coupling reaction with a (hetero)arylboronic acid in a one-pot reaction.
